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  • COSENTYX® for psoriasis

    What is COSENTYX® and how does it work?

    COSENTYX® contains the active substance secukinumab, which is a fully human monoclonal antibody. Monoclonal antibodies are proteins that recognize and bind specifically to certain proteins in the body. A protein called ‘IL-17A’ is present at increased levels in diseases such as psoriasis. COSENTYX® works by neutralizing the activity of IL-17A, which in turn reduces the signs and symptoms of the disease, including pain, itching, and scaly patches.

    How and when do I take COSENTYX®?

    The recommended dose of COSENTYX® is 300 mg, and should be taken as two 150 mg subcutaneous self-injections using the COSENTYX® pre-filled syringe or COSENTYX® SensoReady® pen. Each 300 mg dose is given as two subcutaneous injections of 150 mg.

    At the start of your treatment, you will take your COSENTYX® injections at Weeks 0, 1, 2, 3 and 4, followed by monthly maintenance dosing.

    You and your doctor should decide if you should inject COSENTYX® yourself. It is important to have been trained by your doctor, nurse or pharmacist before injecting yourself. A caregiver, friend, or family member may also give your COSENTYX® injection after proper training.

    Make sure you take COSENTYX® exactly as your doctor has instructed. Check with your doctor, nurse or pharmacist if you are not sure.

    For detailed instructions on how to inject COSENTYX®, see
    “My Injection Steps card” available in the My Resources section of this website.

    Important safety information to read before starting COSENTYX®


    You should store the COSENTYX® SensoReady® pen sealed in its outer box to protect it from light. It should be kept in the refrigerator between 2°C and 8°C. DO NOT FREEZE.

    If necessary, the pre-filled syringe and the SensoReady pen may be stored unrefrigerated for a single period of up to 4 days at room temperature, not above 30°C. Discard the pre-filled syringe or SensoReady pen after 4 days if left unrefrigerated.

    If you accidentally inject more COSENTYX® or sooner than instructed, inform your doctor immediately. In the event of drug overdose, contact your doctor, a member of your health care team, your local hospital emergency department, or regional Poison Control Centre immediately, even if there are no symptoms.

    If you have forgotten to inject a dose of COSENTYX®, take the dose when you remember and return to your regular schedule. Then talk to your doctor to discuss when you should inject the next dose.

    BEFORE you use COSENTYX® talk to your doctor or pharmacist if:

    • - You currently have an infection or if you have long-term or repeated infections
    • - You have tuberculosis. Your doctor should check you for tuberculosis before starting treatment
    • - You ever had an allergic reaction to latex. The needle cap on the COSENTYX® SensoReady® pen and pre-filled syringe contains a derivative of latex
    • - You have Crohn’s disease or ulcerative colitis
    • - You had a recent vaccination or if you will receive a vaccination during treatment with COSENTYX®

    Talk to your doctor or pharmacist immediately if you get any of these symptoms during your COSENTYX® treatment.

    You have worsening symptoms or develop new symptoms of stomach pain or diarrhea.

    Signs or symptoms of a potentially serious infection. These may include:

    • - Fever, flu-like symptoms, muscle aches, night sweats
    • - Feeling tired or short of breath; cough which will not go away
    • - Warm, red and painful skin, or a painful skin rash with blisters
    • - Burning when passing water

    Signs or symptoms of an allergic reaction. These may include:

    • - Chest tightness, difficulty breathing or swallowing
    • - Low blood pressure, which can cause dizziness or light-headedness
    • - Swelling of the face, lips, mouth or throat

    Do not use COSENTYX® if you had a severe allergic reaction to latex, secukinumab or any of the other ingredients of COSENTYX® (trehalose dehydrate, L-histidine/histidine hydrochloride monohydrate, L-methionine, polysorbate 80, water). If you think you may be allergic, talk to your doctor, and ask for advice before using COSENTYX®. Do not take COSENTYX® if you have any signs of infection or an active tuberculosis infection unless you are instructed to by your health care provider.

    COSENTYX® is not recommended for children and adolescents (under 18 years of age) because it has not been studied in this age group.

    Talk to your doctor before using COSENTYX®:

    • - If you are pregnant, think that you may be pregnant or are
    • - planning to have a baby
    • - COSENTYX® is not recommended during pregnancy unless
    • - the benefits clearly outweigh the potential risks
    • - If you are breastfeeding or plan to breastfeed
    • - It is not known if COSENTYX® passes into your breast milk

    COSENTYX® is a medicine that affects your immune system. COSENTYX® may increase your risk of having serious side effects such as infections.

    As with all medicines, patients treated with COSENTYX® may experience side effects. Most of the side effects with COSENTYX® are mild to moderate. The most common side effects include:

    • - Upper respiratory tract infections with symptoms such as sore
    • - throat and stuffy nose (nasopharyngitis, rhinitis)
    • - Cold sores (oral herpes)
    • - Diarrhea
    • - Itchy rash (urticaria)
    • - Runny nose (rhinorrhea)

    The above is not a complete list of side effects; for more complete information, refer to the Consumer Information leaflet available here.

    STOP using COSENTYX® and seek medical help immediately if you experience any of the following, which are signs of an allergic reaction:

    • - Difficulty breathing or swallowing
    • - Swelling of the face, lips, tongue or throat
    • - Severe itching of the skin, with a red rash or raised bumps